Drug Discovery Support

CANTEST Life Sciences provides LC-MS/MS support for drug discovery and development to facilitate discovery screening, lead optimization and lead selection. Specifically, the laboratory supports the bioanalysis of samples resulting from in vitro and in vivo lead optimization screens.

Bioanalytical services support standard preclinical/ clinical drug development, as well as provide input for evaluations in areas such as pharmacology and drug metabolism. The group can assist with metabolite identification and profiling using LC-MS/MS instrumentation; metabolite profiling service includes analysis of plasma, urine and feces from all toxicological species. 

CANTEST Life Sciences' expertise in method development allows for rapid access to LC-MS/MS methods that provide structural information relating to putative metabolites. Early identification of metabolites and metabolic products can provide essential information to drive decision making throughout the drug development process.